Information for foreign students


UNIWERSITY OF WARSAW

1 Pasteura Str., 02-093 Warsaw, Poland, phone: +48 (0)22 822 02 11

41


Subject

Synthesis and Application of Isotopes
in Organic Chemistry, Biochemistry
and Medicine


No / course unit code


Semester

2M

Type of course

Lecture


Teaching hours
 per semester    per week

30      2

ECTS credits

3


Lecturer:

Prof. dr. hab. Marianna Kańska
Room: 230     Phone extn.:509     email: mkanska@chem.uw.edu.pl

Teaching Division:

Organic Chemistry

Educational and
professional goals:

The aim of this course is to familiarize students with various methods used during synthesis of labeled biologically active compounds and their application in organic chemistry, biochemistry and medicine.

Course description:

Synthesis of labelled biologically active compounds: alkanes and cycloalkanes, compounds with double bond, i.e., >C=C<, >C=O, >C=N-, etc.; halogen derivatives, carboxylic acids and their derivatives. Synthesis of compounds labelled with isotopes of iodine. Enzymatic and stereospecific synthesis of biologically active compounds labelled with deuterium, tritium, radiophosphorus, and isotopes of carbon. Application of labelled compounds to study the mechanism of organic and biochemical reactions. Positron Emission Tomography (PET) as a diagnostic method in nuclear medicine. Synthesis of compounds used in PET.

Required background:


Organic Chemistry I and II, Biochemistry and Nuclear Chemistry.

Form of assessment:


Exam

Remarks:

-




Supervisor: Jadwiga Skupinska

Webmaster: Adam Myslinski