Topics of Bachelor's theses

1. "Flow microcells using metal nanoparticles"
Ph.D., D.Sc. Krzysztof Stolarczyk
The aim of this project is to develop a prototype of a flow biofuel cell made of bioelectrodes based on metal nanoparticles and enzymes to power medical devices implanted in patients. The biofuel cell is to use energy sources naturally occurring in body fluids (glucose, dissolved oxygen, etc.) and convert them into electricity.

2. "Oxygen sensor for monitoring the oxygen concentration in the human body"
Ph.D., D.Sc. Krzysztof Stolarczyk
The latest research indicates the possibility of using biofuel as self-supplying devices that do not require an external energy source for operation, thanks to the use of chemical substances contained in the body, converting the chemical energy of redox reactions into electricity, which would be a breakthrough in medicine and implanted devices. A biofuel cell will be used for the construction of the sensor, consisting of a zinc anode and a cathode covered with nanomaterials and laccase, as a self-powered oxygen sensor implanted into the body.

3 "Biofuel cells with the use of three-dimensional bioelectrodes"
Ph.D., D.Sc. Krzysztof Stolarczyk
This project concerns the preparation of a biofuel cell with the use of three-dimensional electrodes. A novelty in the approach to the construction of such biofuel cells is the construction of electrodes consisting in immobilizing enzymes as biocatalysts on a spatial porous carbon material such as porous glassy carbon (RVC, Reticulated Vitreous Carbon). We plan to deposit Ru and Au nanoparticles on its surface as enzyme adsorption centers. Graphene nanotubes and nanoparticles will also be used as porous materials. The biofuel cell is to use energy sources naturally occurring in body fluids (glucose, dissolved oxygen, etc.) and convert them into electricity.

4 "The use of gold nanoparticles as selective drug nanocarriers in the transport of anti-cancer active substances"
Ph.D., D.Sc. Krzysztof Stolarczyk
PhD Elżbieta U. Stolarczyk, Łukasiewicz Research Network - Industrial Chemistry Research Institute Prof. I. Mościcki in Warsaw
Due to their unique physical and chemical properties, gold nanoparticles can be used for the transport and distribution of pharmaceuticals. They are used in gene therapy, in bactericidal and anti-cancer applications. The aim of this project is to develop a method for the synthesis of gold nanoparticles with appropriate drugs and to characterize these systems using various techniques, e.g. voltammetric, spectroscopic, etc.

5. "The use of platinum nanoparticles as nanozymes"
Ph.D., D.Sc. Krzysztof Stolarczyk
Taking advantage of the rapid development of nanotechnology and biotechnology, significant progress has been made in recent years in mimicking enzymatic activities with the use of high-performance nanomaterials, for example, by means of nanozymes with the participation of visible light, highly reactive oxygen species are created. These forms rapidly decompose and kill the bacteria. Therefore, artificial enzymes can one day be used to fight infections as well as treat various cancers. The aim of this project is to prepare nanozymes based on platinum nanoparticles and use them in specific chemical reactions.

Topics of master's theses

1. "Flow micro biofuel cells using metal nanoparticles"
Ph.D., D.Sc. Krzysztof Stolarczyk
The aim of this project is to develop a prototype of a flow biofuel cell made of bioelectrodes based on metal nanoparticles and enzymes to power medical devices implanted in patients. The biofuel cell is to use energy sources naturally occurring in body fluids (glucose, dissolved oxygen, etc.) and convert them into electricity.

2. "Oxygen sensor for monitoring the oxygen concentration in the human body"
Ph.D., D.Sc. Krzysztof Stolarczyk
The latest research indicates the possibility of using biofuels as self-supplying devices that do not require an external energy source for operation, thanks to the use of chemical substances contained in the body, converting the chemical energy of redox reactions into electricity, which would be a breakthrough in medicine and implanted devices. A biofuel cell will be used for the construction of the sensor, consisting of a zinc anode and a cathode covered with nanomaterials and laccase, as a self-powered oxygen sensor implanted into the body.

3. "Biofuel cells with the use of three-dimensional bioelectrodes"
Ph.D., D.Sc. Krzysztof Stolarczyk
This project concerns the preparation of a biofuel cell with the use of three-dimensional electrodes. A novelty in the approach to the construction of such biofuel cells is the construction of electrodes consisting in immobilizing enzymes as biocatalysts on a spatial porous carbon material such as porous glassy carbon (RVC, Reticulated Vitreous Carbon). We plan to deposit Ru and Au nanoparticles on its surface as enzyme adsorption centers. Graphene nanotubes and nanoparticles will also be used as porous materials. The biofuel cell is to use energy sources naturally occurring in body fluids (glucose, dissolved oxygen, etc.) and convert them into electricity.

4. "The use of gold nanoparticles as selective drug nanocarriers in the transport of anti-cancer active substances"
Ph.D., D.Sc. Krzysztof Stolarczyk
Ph.D. Elżbieta U. Stolarczyk, Łukasiewicz Research Network - Industrial Chemistry Research Institute Prof. I. Mościcki in Warsaw
Due to their unique physical and chemical properties, gold nanoparticles can be used for the transport and distribution of pharmaceuticals. They are used in gene therapy, in bactericidal and anti-cancer applications. The aim of this project is to develop a method of synthesizing gold nanoparticles with appropriate drugs and to characterize these systems using various techniques, e.g. voltammetric, spectroscopic, etc.

5.. "The use of platinum nanoparticles as nanozymes"
Ph.D., D.Sc. Krzysztof Stolarczyk
Taking advantage of the rapid development of nanotechnology and biotechnology, significant progress has been made in recent years in mimicking enzymatic activities with the use of high-performance nanomaterials, for example, by means of nanozymes with the participation of visible light, highly reactive oxygen species are created. These forms rapidly decompose and kill the bacteria. Therefore, artificial enzymes can one day be used to fight infections as well as treat various cancers. The aim of this project is to prepare nanozymes based on platinum nanoparticles and use them in specific chemical reactions.

5. "Enzymatic glutamate biosensor based on gold nanostructured electrodes"
Ph.D., DScKrzysztof Stolarczyk
Ph.D., D.Sc., Eng. Marcin Urbanowicz (Laboratory of Biosensors and Analytical Microsystems Department I, Institute of Biocybernetics and Biomedical Engineering M. Nałęcza, Polish Academy of Sciences)
The aim of the thesis is to develop an electrochemical glutamate biosensor, the bioreceptor layer of which will be glutamate oxidase immobilized on the sensor surface. The design of the biosensor will be based on gold electrodes, the surface of which will be nanostructured to increase sensitivity. Various techniques of enzyme immobilization will be used for the biofunctionalization of the gold electrodes: covalent and cross-linking.

6. "Hybrid enzymatic-inorganic micro - and nanoflowers"
Ph.D., DScKrzysztof Stolarczyk
Ph.D., D.Sc., Eng. Kamila Sadowska (Laboratory of Biosensors and Analytical Microsystems Department I, Institute of Biocybernetics and Biomedical Engineering M. Nałęcza, Polish Academy of Sciences)
The aim of the project is to obtain and use enzymatic-metallic nanostructures as receptor materials. Such structures can be used as catalysts for various processes, as well as for the construction of biosensors or biofuel cells. Structural and electrochemical tests of the created systems will be carried out. On this basis, the influence of the shape and size of microflowers on the electro-catalytic ability of the system will be determined. As part of the diploma thesis, a method of obtaining nano-scale structures will be developed.